Recently,Professor Yuichi Sugiyama from University of Tokyo, a leading scientist in the area of drug transporter visited SIMM and represented a brilliant lecture about transporters and their effects on ADME properties of drugs.
Due to the important roles played in ADME processes of drugs, transporters are drawing more and more attention nowadays. A seminar concerning about drug transporters and their effects was held in Chenggu hall of SIMM, co-hosted by Shanghai Center for Pharmacokinetics and Drug Metabolism Research, Shanghai DMPK Discussion Group and Division of Drug Metabolism, Shanghai Pharmacological Society.
For this seminar, Professor Yuichi Sugiyama, former chairman of the International Society for the Study of Xenobiotics (ISSX) was invited to represent a lecture. Professor Yuichi Sugiyama is one of the pioneers and has been doing research on drug transporters for 30 years and gained many glorious achievements in respect of drug-transporter interaction and transporter model construction, which enhanced the research level of transporters greatly. His wonderful lecture “Drug Transporters in the New Drug Discovery and Development” introduced both the fundamentals and development frontiers of drug transporters, relating to several aspects including synergistic effect of biliary uptake and efflux transporters, the rate-limiting factors in hepatic clearance of drug and polymorphism of OATPs.
Besides the scholars and students of SIMM, many researchers from pharmaceutical companies, like GlaxoSmithKline, Novartis, Roche, Pfizer and WuXi PharmaTech, were attracted to the seminar. Thanks to the interesting lecture and the heating discussion, the audience benefited a lot from this seminar.