Researchers Disrupt cGAS-DNA Phase Separation by De Novo Design of Allosteric Inhibitors: A Potential Therapeutic Strategy

In a study published in Nature Communications, a research team led by XU Yechun from the Shanghai Institute of Materia Medica (SIMM) of the Chinese Academy of Sciences (CAS) rep...

Researchers Develop Tracheal Targeted Nanogrid Drug Delivery Systems Visualized by Three-dimensional Pathological Mapping

In a study published in ACS Nano, a research team led by YIN Xianzhen from the Lingang Laboratory and ZHANG Jiwen from the Shanghai Institute of Materia Medica (SIMM) of the Chi...

NMRExtractor: Leveraging Large Language Models to Construct an Experimental NMR Database from Open-source Scientific Publications

In this work, the researchers developed NMRExtractor by fine-tuning Mistral-7B-instruct LLM on a curated dataset of human-annotated NMR examples. The model was optimized to inte...