| HD is caused by the mutation of the HTT gene encoding the mutant HTT protein ( mHTT ) with expanded polyglutamine tract ( polyQ ) .A research paper entitled “ Targeting GPR52 lowers mutant HTT levels and rescues Huntington ’ s disease-associated phenotypes ” was published in Brain . The work was conducted by Fudan University and the Shanghai Institute of Materia Medica ( SIMM ) of the Chinese Academy of Sciences . In this study . |
