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Scientists Find Potential Drug Target for the Treatment of Huntington’s Disease
HD is caused by the mutation of the HTT gene encoding the mutant HTT protein ( mHTT ) with expanded polyglutamine tract ( polyQ ) .A research paper entitled “ Targeting GPR52 lowers mutant HTT levels and rescues Huntington ’ s disease-associated phenotypes ” was published in Brain . The work was conducted by Fudan University and the Shanghai Institute of Materia Medica ( SIMM ) of the Chinese Academy of Sciences . In this study .
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