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The many and varied uses of the lipid cubic phase in membrane structural and functional biology research
 
Big small molecule pharmaceuticals:cancer vaccines and dendrimers
 
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Simultaneous targeting of PI3Kδ and a PI3Kδ-dependent MEK1/2-Erk1/2 pathway for therapy in pediatric B-cell acute l...
B-cell acute lymphoblastic leukemia ( B-ALL ) is predominantly a childhood diseasewith approximately 75% of patients younger than 6 years of age .Which displays distinct binding mode with p110 δ and blocks constitutively active or stimulus-induced PI3K δ signaling .X-370 binds to PI3Kdelta with a distinct mode and selectively inhibits its activity in a ATP-competitive manner.
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