| Multidrug resistance ( MDR ) mediated by P-glycoprotein ( P-gp ) is a principal obstacle in anti-cancer treatment .And utilized the readily available building blocks ( natural amino acids ) to assemble allylic-supported macrolides that would be difficult or impossible to obtain by other methods .Modular Biomimetic Strategy and C-H Activation Method to Create Macrolides P-glycoprotein Inhibitors ( Image by SIMM ) Contact : Prof . YANG Weibo Email : yweibo @ simm . ac . cn ( Credit : YANG Weibo ). |
