| G protein-coupled receptor kinases （ GRKs ） play pivotal roles in the desensitization of G protein-coupled receptors ( GPCRs ) signaling .CAS made progresses in discovering the key components for the rhodopsin / GRK1 interaction and provide a framework for understanding GRK-mediated desensitization of GPCRs . The finding has been published in the Cell Research . GPCRs play fundamental roles in a broad spectrum of physiological processes and are involved in blood-related diseases . |
