| Short-chain fatty acids sit at the crossroads of multiple metabolic pathways and play important roles in diverse cellular processes .However , key elements for regulating this physiology-relevant pathway remain unknown , hindering the functional studies of this modification in diverse biological systems .These Kbhb substrates are enriched in proteins associated with diverse nuclear biological processes such as RNA metabolism , chromatin organization and DNA repair , which is quite different from the other type of PTMs such as lysine acetylation . |
