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Meclofenamic acid selective inhibition of FTO demethylation over ALKBH5
A research team of Shanghai Institute of Materia Medica(CAS), Peking University and Fudan University has identified a non-steroidal, anti-inflammatory drug meclofenamic acid (MA) that could highly selectively inhibit FTO demethylation over ALKBH5. Drs. YANG Caiguang, Cheng Luo and Guifang Jia conceived this project with the help from Dr. ZHOU Hu and GAN Jianhua.
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