CN |CAS  
 
  Home | Links | Site map
 
Home About Us News Organization Research Faculty Publication Education&Trainning Contact
  Research
Location: Home > Research
 
 
Research
Target
Discovery
Development
Translation
 
Laggeric acid, a novel seco-eudesmanesesquiterpenoid from Laggeracrispata
Update time: 2014-07-23
Close
Text Size: A A A
Print

Laggeracrispata (Vahl) Hepper&J.R.I.Wood (=Laggerapterodonta (DC.)Benth.,Asteraceae) was known as “ChouLing Dan” in Chinese meaning an odorouspanacea, and its decoction showed to have bioactivities of anti-leukemia, antibacterial, anti-inflammatory, and anti-malarial. In the last decades, numbers of constituents, such as monoterpenes, sesquiterpenes, cyclitols, and flavonoids, were reported from L. crispate and other species of Laggera.

As a continuing interest in the antiviral ingredient of Chinese traditional medicines, Researchers from Prof.Tan Changheng’s group in Shanghai Institute of Materia Medica, CAS conducted a phytochemical investigation on the plant, which led to the isolation of laggeric acid (1), a novel 4,5-seco-eudesmane sesquiterpene acid, along with 19 known compounds comprising five flavonoids, eight eudesmane sesquiterpenoids and five lignan.The result has been published online on “J Asian Nat Prod Res” (DOI:10.1080/10286020.2013.867850)

 
weimoban
About Us News Research Faculty Education&Trainning Organization Contact
Brief Introduction
History
Address from the Director
Directors
Administration
Research
Events
Int'l cooperation
Target
Discovery
Development
Translation
Academician
PI
Graduate Students
Post Graduate Students