Shanghai Institute of Material Medical Chinese Academy of Sciences

Biography

De-an Guo was graduated with his Ph.D. degree of pharmacognosy from Beijing Medical University in 1990. He currently serves as director of Research Center for TCM Modernization and National Engineering Laboratory for TCM Standardization Technology. His research mainly focuses on the quality control and elaboration of pharmacopoeia standards for Chinese herbal medicines. To date, he has published over 700 academic papers, among which 500 plus are cited in SCI journals with 13000 citations.

Education

1979.09 - 1983.07 Undergraduate in Changchun College of Chinese Medicine

1984.09 - 1987.07 Graduate student in West-China Medical University

1987.09 - 1990.07 Ph.D candidate in Beijing Medical University

1993.06 - 1996.10 Postdoctoral Research Fellow in Texas Tech University

Work Experience

1983.08 - 1984.07 Teaching assistant in Inner Mongolia Ethnic Medical College

1990.08 - 1993.06 Assistant professor in Beijing Medical University

1996.10 - 2005.02 Associate professor and professor in Beijing Medical University

2005.03 – present Professor in Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Research Directions

1. Phytochemical analysis of Chinese Materia Medica

2. Quality standard elaboration of Chinese Materia Medica

Grants & Research Projects

Achievements

1.Comprehensive analysis method for traditional Chinese medicines was developed to facilitate its deep understanding of chemical complexity, which was granted as the second-grade prize of the National Natural Science Award of China.

2.Holistic quality standard system of traditional Chinese medicines was constructed and widely applied in main stream Pharmacopoeias like Chinese Pharmacopoeia, United States Pharmacopoeia and European Pharmacopoeia, as well as in TCM industry, which was conferred as the second-grade prize of National Science and Technology Progress Award of China.

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Social Titles

1.Editor, associate editor or editorial board member of 18 international journals as World Journal of Traditional Chinese Medicine, Acta Pharmaceutica Sincia B, Acta Pharmacologica Sinica, Phytochemistry, Fitoterapia, Phytochemical Analysis, etc.

2.Chair of Natural Medicine Committee of Chinese Pharmacopoeia, Chair of East-Asia Expert Panel of United States Pharmacopoeia, Expert member of European Pharmacopoeia.

3.Chair of Expert Committee, “National TCM Standardization Plan”, China Development and Reform Commission and State Administration of Traditional Chinese Medicine.

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Awards & Honors

1.Natural Science Award, Ministry of Education, 1stgrade, 2005;

2.Natural Science Award, Ministry of Education, 1stgrade, 2007;

3.Norman Farnsworth Excellence in Botanical Research Award, American Botancial Council, 2012;

4.National Natural Science Award, 2nd grade, 2012;

5.Cheung An Tak International Award for Outstanding Contribution to Chinese Medicine, 2015;

6.Varo Tyler Prize, American Society of Phamracognosy, 2016;

7.National Scientific and Technological Progress Award, 2nd grade, 2016;

8.National Innovation and Contending Prize, 2017;

9.Ho Leung Ho Lee Prize for Scientific and Technological Progress, 2017;

10.Outstanding Contribution Prize for China Standard, 2018.

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Pubilcations

Full Publication List

Selected Publications

1.Xuan Liu, Wanying Wu, Baohong Jiang, Min Yang, De-an Guo*, Pharmacological tools for the development of traditional Chinese medicine, TRENDS PHARMACOL SCI, 2013, 34(11): 620-628.

2.De-an Guo*, Wanying Wu, Min Ye, Xuan Liu, Geoffrey Cordell, A holistic approach to the quality control of traditional Chinese medicines, SCIENCE, 2015, 347 (6219 Suppl), S29-31.

3.Xiaojian Shi, Wenzhi Yang, Shi Qiu, Changliang Yao, Yao Shen, Qirui Bi, Min Yang, Wanying Wu, De-an Guo*. An in-source multiple collision-neutral loss filtering based nontargeted metabolomics approach for comprehensive analysis of malonyl-ginsenosides from Panax ginseng, P. quinquefolius, and P. notoginseng, ANAL CHIM ACTA, 2017, 952: 59-70.

4.QinHao Jin, JianQing Zhang, JinJun Hou, Min Lei, C Liu, X Wang, Y Huang, S Yao, BY Hwang, WY Wu, DA Guo. Novel C-17 spirost protostane-type triterpenoids from Alisma plantago-aquatica with anti-inflammatory activity in Caco-2 cells. ACTA PHARMACEUT SIN B, 2019, 9(4): 809-818.

5.Chang-liang Yao, Jian-qing Zhang, Jia-yuan Li, Wen-long Wei, Shi-fei Wu and De-an Guo*, Traditional Chinese Medicine (TCM) as a source of new anticancer drugs. NAT PROD REP, 2021 Jan 29. PMID: 33511969 doi: 10.1039/d0np00057d.

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