1.Lulu Jiang, Sixiu Liu, Xinglong Jia, Qinting Gong, Xin Wen, Weiwei Lu, Jintong Yang, Xinyuan Wu, Xuan Wang, Yanrui Suo, Yilin Li, Motonari Uesugi, Zhi-bei Qu, Minjia Tan*, Xiaojie Lu* and Lu Zhou*，ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries，J.Am.Chem.Soc. 2023, https://doi.org/10.1021/jacs.3c08852. PMID: 37857329

2.Wen X, Zhang M, Duan Z, Suo Y, Lu W, Jin R, Mu B, Li K, Zhang X, Meng L, Hong Y, Wang X, Hu H, Zhu J, Song W, Shen A, Lu X. Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1H)-one Focused DNA-Encoded Library. J Med Chem. 2023，doi: 10.1021/acs.jmedchem.2c02129. PMID: 37552553.

3.Mengnisa Seydimemet, Yixuan Yang, Yuhan Lv, Jiaxiang Liu, Ziqin Yan, Yujun Zhao*, Xuan Wang*, and Xiaojie Lu* Design, Construction, and Screening of Diversified Pyrimidine-Focused DNA-Encoded Libraries，ACS Medicinal Chemistry Letters， 2023，DOI: 10.1021/acsmedchemlett.3c00205. PMID: 37583819 

4.Chang Shen, Peijia Xu, Changfa Zhang, Zhaoming Su, Bin Shan, Rui Li, Qibang Sui, Keke Zhang, Zhengyang Chen, Jingyi Zhou, Xiaojie Lu, Kaixian Chen, Mingyue Zheng, Sulin Zhang*, and Hui Hou*Structure–Activity Relationship Study of 1H-Pyrrole-3-carbonitrile Derivatives as STING Receptor Agonists, ACS Med. Chem. Lett. 2023, doi: 10.1021/acsmedchemlett.3c00208. PMID: 37583816

5.He S, Li L*, Jin R, Lu X. * Biological Function of Pin1 in Vivo and Its Inhibitors for Preclinical Study: Early Development, Current Strategies, and Future Directions. J Med Chem. 2023 Jul 12. doi: 10.1021/acs.jmedchem.3c00390. PMID: 37438908

6. Chen L, Fan Z, Chang J, Yang R, Hou H, Guo H, Zhang Y, Yang T, Zhou C, Sui Q, Chen Z, Zheng C, Hao X, Zhang K, Cui R, Zhang Z, Ma H, Ding Y, Zhang N, Lu X, Luo X, Jiang H, Zhang S, Zheng M. Sequence-based drug design as a concept in computational drug design. Nat Commun. 2023 Jul 14;14(1):4217. doi:10.1038/s41467-023-39856-w. PMID: 37452028; PMCID: PMC10349078.

7.Bao Y, Xing M, Matthew N, Chen X, Wang X*, Lu X*. Macrocyclizing DNA-Linked Peptides via Three-Component Cyclization and Photoinduced Chemistry. Org Lett. 2023 Jun 29. doi: 10.1021/acs.orglett.3c01817. Epub ahead of print. PMID:37382883.

8.Zhao Q, Bao Y, Niu D*, Wang X*, Lu X. * The Development of DNA-Compatible S-Glycosyl Transformations. Org Lett. 2023 Jun 26. doi:10.1021/acs.orglett.3c01799. Epub ahead of print. PMID: 37358352.

9.Zhang Z, Wang G, Li R, Ni L, Zhang R, Cheng K, Ren Q, Kong X, Ni S, Tong X, Luo L, Wang D, Lu X, Zheng M, Li X. Tora3D: an autoregressive torsion angle prediction model for molecular 3D conformation generation. J Cheminform. 2023 Jun 7;15(1):57. doi: 10.1186/s13321-023-00726-8. PMID: 37287071; PMCID: PMC10245430.

10.Guo AD, Yan KN, Hu H, Zhai L, Hu TF, Su H, Chi Y, Zha J, Xu Y, Zhao D, Lu X, Xu YJ, Zhang J, Tan M, Chen XH. Spatiotemporal and global profiling of DNA-protein interactions enables discovery of low-affinity transcription factors. Nat Chem.2023 Jun;15(6):803-814. doi: 10.1038/s41557-023-01196-z. Epub 2023 Apr27. PMID: 37106095.

11.Ling X, Liu S, Yang Y, Dong Q, Marcaurelle LA, Huang W, Ding Y*, Wang X*, Lu X*. Modular Click Assembly DNA-Encoded Glycoconjugate Libraries with on-DNA Functional Group Transformations. Bioconjug Chem. 2023 Mar 24. doi:10.1021/acs.bioconjchem.3c00068. Epub ahead of print. PMID: 36961996.

12.Wen X, Wu X, Jin R, Lu X*. Privileged heterocycles for DNA-encoded library design and hit-to-lead optimization. Eur J Med Chem. 2023 Feb 15;248:115079.doi: 10.1016/j.ejmech.2022.115079. Epub 2023 Jan 14. PMID: 36669370.

13.Suo Y, Xu M, Sun M, Lu W, Wang X*, Lu X*. Ruthenium-Mediated [2 + 2 + 2] Cyclization: A Route to Forge Indane and Isoindoline Core and Its Application in DNA-Encoded Library Technology. Org Lett. 2022 Dec 16;24(49):9092-9096. doi:10.1021/acs.orglett.2c03759. Epub 2022 Dec 7. PMID: 36475704.

14.Zhang Y, Xia S, Shi WX, Lin B, Su XC, Lu W, Wu X, Wang X, Lu X, Yan M, Zhang XJ. Radical C-H Sulfonation of Arenes: Its Applications on Bioactive and DNA-Encoded Molecules. Org Lett. 2022 Nov 4;24(43):7961-7966. doi:10.1021/acs.orglett.2c03077. Epub 2022 Oct 24. PMID: 36278920.

15.Li L, Su M, Lu W, Song H, Liu J, Wen X, Suo Y, Qi J, Luo X, Zhou YB, Liao XH*, Li J*, Lu X*. Triazine-Based Covalent DNA-Encoded Libraries for Discovery of Covalent Inhibitors of Target Proteins. ACS Med Chem Lett. 2022 Aug15;13(10):1574-1581. doi: 10.1021/acsmedchemlett.2c00127. PMID: 36262386; PMCID:PMC9575176.

16.Wu X, Chen Y, Lu W, Jin R, Lu X*. Quantitative Validation and Application of the Photo-Cross-Linking Selection for Double-Stranded DNA-Encoded Libraries. Bioconjug Chem. 2022 Oct 19;33(10):1818-1824. doi:10.1021/acs.bioconjchem.2c00421. Epub 2022 Oct 5. PMID: 36197318.

17.Wang X, Lu X. Ruthenium-Promoted On-DNA C-H Activation Reaction. Methods Mol Biol. 2022; 2541:63-66. doi: 10.1007/978-1-0716-2545-3_10. PMID: 36083545.

18.Wang X, Lu X. Palladium-Promoted On-DNA Heck Reactions. Methods Mol Biol. 2022; 2541:55-61. doi: 10.1007/978-1-0716-2545-3_9. PMID: 36083544.

19.Lu X, Wang X. On-DNA Pd and Cu-Promoted C-N Cross-Coupling Reactions. Methods Mol Biol. 2022; 2541:49-54. doi: 10.1007/978-1-0716-2545-3_8. PMID:36083543.

20. Liu W, Bai X, Song L, Wang X*, Lu X*. Constructing Head-to-Tail Cyclic Peptide DNA-Encoded Libraries Using Two-Directional Synthesis Strategy. Bioconjug Chem. 2022 Apr 20;33(4):560-565. doi: 10.1021/acs.bioconjchem.2c00078. Epub 2022 Mar 11. PMID: 35274526.

21.Qi J, Liu S, Seydimemet M, Wang X*, Lu X*. A General Set of DNA-Compatible Reactions for Preparing DNA-Tagged Multisubstituted Pyrroles. Bioconjug Chem.2021 Nov 17;32(11):2290-2294. doi: 10.1021/acs.bioconjchem.1c00427. Epub 2021 Oct 26. PMID: 34699185.

22.Lin B, Lu W, Chen ZY, Zhang Y, Duan YZ, Lu X, Yan M, Zhang XJ. Enhancing the Potential of Miniature-Scale DNA-Compatible Radical Reactions via an Electron Donor-Acceptor Complex and a Reversible Adsorption to Solid Support Strategy. Org Lett. 2021 Oct 1;23(19):7381-7385. doi: 10.1021/acs.orglett.1c02562. Epub 2021 Sep 21. PMID: 34546064.

23.Yang P, Wang X, Li B, Yang Y, Yue J, Suo Y, Tong H, He G, Lu X*, Chen G*. Streamlined construction of peptide macrocycles via palladium-catalyzed intramolecular S-arylation in solution and on DNA. Chem Sci. 2021 Mar 11;12(16):5804-5810. doi: 10.1039/d1sc00789k. PMID: 34168804; PMCID: PMC8179660.

24.Wang X, Liu J, Yan Z, Liu X, Liu S, Suo Y, Lu W, Yue J, Chen K, Jiang H, Zhao Y*, Zheng M*, Dai D*, Lu X*. Diversified strategy for the synthesis of DNA-encoded oxindole libraries. Chem Sci. 2021 Jan 4;12(8):2841-2847. doi:10.1039/d0sc06696f. PMID: 34164048; PMCID: PMC8179416.

25.Shan J, Ling X, Liu J, Wang X*, Lu X*. DNA-encoded CH functionality via photoredox-mediated hydrogen atom transformation catalysis. Bioorg Med Chem. 2021 Jul 15;42:116234. doi: 10.1016/j.bmc.2021.116234. Epub 2021 May 28. PMID: 34098191.

26.Ling X, Lu W, Miao L, Marcaurelle LA, Wang X*, Ding Y*, Lu X*. Divergent On-DNA Transformations from DNA-Linked Piperidones. J Org Chem. 2022 Feb 18;87(4):1971-1976. doi: 10.1021/acs.joc.1c00670. Epub 2021 May 7. PMID:33960188.

27.Liu C, Zhou F, Yan Z, Shen L, Zhang X, He F, Wang H, Lu X, Yu K, Zhao Y, Zhu D. Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy. Br J Pharmacol. 2021 Jul;178(13):2651-2670. doi: 10.1111/bph.15457. Epub 2021 May 4. PMID:33768523.

28.Liu S, Qi J, Lu W, Wang X*, Lu X*. Synthetic Studies toward DNA-Encoded Heterocycles Based on the On-DNA Formation of α,β-Unsaturated Ketones. Org Lett.2021 Feb 5;23(3):908-913. doi: 10.1021/acs.orglett.0c04118. Epub 2021 Jan 14. Erratum in: Org Lett. 2022 Jul 1;24(25):4716. PMID: 33444029.

29.Wen X, Duan Z, Liu J, Lu W, Lu X*. On-DNA Cross-Dehydrogenative Coupling Reaction toward the Synthesis of Focused DNA-Encoded Tetrahydroisoquinoline Libraries. Org Lett. 2020 Aug 7; 22(15):5721-5725. doi: 10.1021/acs.orglett.0c01565. Epub 2020 Jul 9. PMID: 32644810.

30.Li K, Liu X, Liu S, An Y, Shen Y, Sun Q, Shi X, Su W, Cui W, Duan Z, Kuai L, Yang H, Satz AL, Chen K, Jiang H, Zheng M*, Peng X*, Lu X*. Solution-Phase DNA-Compatible Pictet-Spengler Reaction Aided by Machine Learning Building Block Filtering. iScience. 2020 Jun 26;23(6):101142. doi: 10.1016/j.isci.2020.101142. Epub 2020 May 7. PMID: 32446221; PMCID: PMC7243192.

31.Qu Y, Liu S, Wen H, Xu Y, An Y, Li K, Ni M, Shen Y, Shi X, Su W, Cui W, Kuai L, Satz AL, Yang H, Lu X*, Peng X*. Palladium-mediated Suzuki-Miyaura Cross-Coupling Reaction of Potassium Boc-protected aminomethyltrifluoroborate with DNA-Conjugated aryl bromides for DNA-Encoded chemical library synthesis. Biochem Biophys Res Commun. 2020 Dec 3;533(2):209-214. doi: 10.1016/j.bbrc.2020.04.027. Epub 2020 May 4. PMID: 32376009.

32.Wu W, Sun Z, Wang X, Lu X, Dai D. Construction of Thiazole-Fused Dihydropyrans via Formal [4 + 2] Cycloaddition Reaction on DNA. Org Lett. 2020 Apr 17;22(8):3239-3244. doi: 10.1021/acs.orglett.0c01016. Epub 2020 Apr 3. PMID: 32243186.

33.Wang DY, Wen X, Xiong CD, Zhao JN, Ding CY, Meng Q, Zhou H, Wang C, Uchiyama M, Lu XJ*, Zhang A*. Non-transition Metal-Mediated Diverse Aryl-Heteroatom Bond Formation of Arylammonium Salts. iScience. 2019 May 31;15:307-315. doi: 10.1016/j.isci.2019.04.038. Epub 2019 May 3. PMID: 31102996; PMCID: PMC6525302.

34.Wang X, Sun H, Liu J, Zhong W, Zhang M, Zhou H, Dai D*, Lu X*. Palladium-Promoted DNA-Compatible Heck Reaction. Org Lett. 2019 Feb 1;21(3):719-723. doi:10.1021/acs.orglett.8b03926. Epub 2019 Jan 24. PMID: 30676761.

35.Li H, Sun Z, Wu W, Wang X, Zhang M, Lu X, Zhong W, Dai D. Inverse-Electron-Demand Diels-Alder Reactions for the Synthesis of Pyridazines on DNA. Org Lett. 2018 Nov 16;20(22):7186-7191. doi: 10.1021/acs.orglett.8b03114. Epub 2018 Oct 26. PMID: 30365326.

36.Wang X, Sun H, Liu J, Dai D, Zhang M, Zhou H, Zhong W*, Lu X*. Ruthenium-Promoted C-H Activation Reactions between DNA-Conjugated Acrylamide and Aromatic Acids. Org Lett. 2018 Aug 17;20(16):4764-4768. doi: 10.1021/acs.orglett.8b01837. Epub 2018 Aug 6. PMID: 30080052.

37.Gang Yao*, Xiaojie Lu, Christopher B. Phelps, Ghotas Evindar, Chapter 7, DNA encoded library technology, page 153-183. “Chemical and Biological Synthesis: Enabling Approaches for Understanding Biology”, Royal Society Chemistry, 2018.

38.Xiaojie Lu*, Sarah Roberts, George J. Frankline and Christopher P. Davie, “On-DNA Pd and Cu promoted C-N Cross-Coupling Reactions”, MedChemComm, 2017, 8, 1614 1617 (2017 Hot Articles in MedChemComm).

39.Xiaojie Lu*, Lijun Fan*, Christopher B. Phelps, Christopher P. Davie, and Christine P. Donahue, “Ruthenium Promoted On-DNA Ring-Closing Metathesis and Cross-Metathesis”, Bioconjugate Chem., 2017, 28, 1625–1629 (This article was highlighted by C&EN, “Making macrocyclic compounds for DNA-encoded libraries”, C&EN online July 6, 2017).

40.Baptiste Thomas, Xiaojie Lu*, William Birmingham, Kun Huang, Peter Both, Juana Reyes Martinez, Robert Young*, Christopher Davie, Sabine Flitsch*, “Application of Biocatalysis to on-DNA Carbohydrate Library Synthesis”, ChemBioChem, 2017, 18, 858-863. (This article was selected as the cover picture for special issue: DNA encoded chemistry, ChemBioChem, 2017, 18, 825.) 

41.Xiaojie Lu and Li Deng*, “Hydrogen Bonding-Mediated Cooperative Organocataoysis by Modified Cinchona Alkaloids” Cooperative Catalysis. Ed. Peters, R. Weinheim Germany: Wiley-VCH Gmbh & Co, 2015. 145-169.

42.Lin Hu, Xiaojie Lu and Li Deng*, “Catalytic Enantioselective Peroxidation of α,β-Unsaturated Aldehydes for the Asymmetric Synthesis of Biologically Important Chiral Endoperoxides” J. Am. Chem. Soc., 2015, 137, 8400-8403.

43.Xiaojie Lu and Li Deng*, “Catalytic Asymmetric Peroxidation of  a,b-Unsaturated Nitroalkenes by a Bifunctional Organic catalyst”, Org. Lett., 2014, 16, 2358-2361. 

44.Xiaojie Lu, Yan Liu, Bingfeng Sun, Brittany Cindric, and Li Deng*, “Catalytic enantioselective peroxidation of  a,b-unsaturated ketones”, J. Am. Chem. Soc., 2008, 130, 8134-8135(This communication was highlighted by JACS Select # 7 : Organocatalysis in Organic Synthesis. Guest Editor: Louis S. Hegedus J. Am. Chem. Soc., 2009, 131, 15075-15077).

45.Xiaojie Lu and Li Deng*, “Asymmetric aza-Michael reactions of a,b-unsaturated ketones with bifunctional organic catalysts”, Angew. Chem. Int. Ed. 2008, 47, 7710-7713. 

46.Ravi P. Singh, Keith Bartelson, Yi Wang, Heng Su, Xiaojie Lu and Li Deng*, “Enantioselective Diels-Alder reaction of simple a,b-unsaturated ketones with a Cinchona Alkaloid catalyst”, J. Am. Chem. Soc., 2008, 130, 2422-2423.