WANG jie
Principal Investigator
Small-Molecule Drug Research Center
Personal Homepage
CONTACT
jiewang@simm.ac.cn
021-20231000-4081
201203
555 Zu Chong Zhi Road, Zhang Jiang Hi-Tech Park, Pudong, Shanghai, P.R.China
Biography
Jie received his undergraduate degree in chemistry from Nanjing University in 2009. Upon graduation, he moved to Shanghai Institute of Organic Chemistry and earned his Ph.D. in 2014. After a short stay in the same group, he moved to the US in 2015 pursuing his postdoctoral studies at Scripps Research. In October of 2019, he moved back to China and joined the faculty at Shanghai Institute of Materia Medica, Chinese Academy of Sciences.
Education:
2004.09-2009.06 Nanjing University, B.S. in Chemistry
2009.09-2014.06 Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Ph.D. in Organic Chemistry
Work Experience:
2014.07-2015.04 Research Associate, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
2015.05-2019.10 Postdoctoral Associate, Scripps Research
2019.10-Present Principal Investigator, Shanghai Institute of Materia Medica, Chinese Academy of Sciences.
Research Directions
Synthesis, structural modification and target identification and verification of natural products.
Grants & Research Projects
Achievements
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Social Titles
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Awards & Honors
2007 Renming Scholarship of Nanjing University
2007 Renming Scholarship of Nanjing University
2013 Merit Student of Chinese Academy of Sciences
2013 National Scholarship of Ph.D. candidate
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Pubilcations
Full Publication List
Selected Publications
1.Wang,J.; Sun, B.-F.; Cui, K.; Lin, G.-Q. An Efficient Total Synthesis of (–)-Epothilone B. Org. Lett. 2012, 14, 6354–6357.
2.Wang,J.; Chen, S.-G.; Sun, B.-F.; Lin, G.-Q.; Shang Y.-J. Collective Total Synthesis of Englerin A and B, Orientalol E and F, and Oxyphyllol: Application of the Organocatalytic [4+3] Cycloaddition Reaction. Chem. Eur. J. 2013, 19, 2539–2547.
3.Wang, J.; Sun, W.-B.; Li, Y.-Z.; Wang, X.; Sun, B.-F.; Lin G.-Q.; Zou J.-P. A Concise Formal Synthesis of Platencin. Org. Chem. Front. 2015, 2, 674–676.
4.Wang, J.; Qin, T.; Chen, T.-G.; Wimmer, L.; Edwards, J. T.; Cornella, J.; Vokits, B.; Shaw, S. A.; Baran, P. S. Nickel-Catalyzed Cross-Coupling of Redox-Active Esters with Boronic Acids. Angew. Chem. Int. Ed. 2016, 55, 9676–9679.
5.Li, C.;* Wang, J.;* Barton L. M.; Yu, S.; Tian, M.; Peters, D. S.; Kumar, M.; Yu, A. W.; Johnson, K. A.; Chatterjee, A. K.; Yan, M.; Baran, P. S. Decarboxylative Borylation. Science 2017, 356, eaam7355. (*Contributed equally)
6.Wang, J.;* Lundberg, H.;* Asaia, S.; Martin-Acosta, P.; Chen, J. S.; Brown, S.; Farrell, W.; Dushin, R.; O’Donnell, C. J.; Ratnayake, A. S.; Richardson, P.; Liu, Z.; Qin, T.; Blackmond, D. G.; Baran, P. S. Kinetically Guided Radical-Based Synthesis of C(sp3)-C(sp3) Linkages on DNA. Proc. Natl. Acad. Sci. U. S. A. 2018, 115, E6404–E6410. (*Contributed equally)
7.Wang, J.;* Shang, M.;* Lundberg, H.; Feu, K. S.; Hecker, S. J.; Qin, T.; Blackmond, D. G.; Baran, P. S. Cu-Catalyzed Decarboxylative Borylation. ACS Catal. 2018, 8, 9537–9542. (*Contributed equally)
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