The Sixth Annual Conference of Pan-Balkan Alliance of Natural Products and Drug Discovery Associations and the 2025 Seminar of UNESCO Regional Network of Natural Products Chemistry held at SIMM, CAS

The Sixth Annual Conference of Pan-Balkan Alliance of Natural Products and Drug Discovery Associations and the 2025 Seminar of UNESCO Regional Network of Natural Products Chemistry was held at the Niudun Road new campus of SIMM from October 26 to ...

2025-11-06 All →

Researchers Unveiled Conformation-Selective “Valve Model” for Norepinephrine Transporter Regulation

In a study published in Cell, researchers from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences and the Lingang Laboratory, together with collaborators, have unveiled a conformation-selective allosteric regulation mechanism of...

2025-10-29 All →

Researchers Reveal Dual-Target Mechanism of New Drug BGT-002 for Treating Metabolic Dysfunction-Associated Steatohepatitis

In a study published in Cell Metabolism, a research team led by LI Jingya, NAN Fajun from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences, in collaboration with DING Yanhua from Jilin University and other partners, repo...

2025-10-23 All →

Researchers Discover Potent Oral Sialylation Inhibitor That Enhances Immunotherapy for Pancreatic Ductal Adenocarcinoma

In a study published in ACS Central Science, a research team led by YU Biao from the Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, and GONG Likun from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences, d...

2025-10-14 All →

Ultrasound-Activatable Lipid Nanoparticle for Improved mRNA Vaccine Cancer Therapy

In a study published in Journal of Controlled Release, a research team led by ZHANG Jiwen from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences used ectoine, a natural stabilizer, to preserve milk-derived EVs (mEVs) through ly...

2025-10-11 All →

Lyophilization Technique Stabilizes Extracellular Vesicles for Effective Dry Eye Treatment

Dry eye disease (DED) is a common condition that affects millions of people worldwide, leading to ongoing eye discomfort and blurred vision. Although extracellular vesicles (EVs) have shown potential as a treatment, their clinical use has been hin...

2025-08-29 All →