Lyophilization Technique Stabilizes Extracellular Vesicles for Effective Dry Eye Treatment

Dry eye disease (DED) is a common condition that affects millions of people worldwide, leading to ongoing eye discomfort and blurred vision. Although extracellular vesicles (EVs) have shown potential as a treatment, their clinical use has been hin...

2025-08-29 All →

Shanghai Institute of Materia Medica Conducts Nucleic Acid Drug Research Aboard China's Space Station

On July 15, 2025, the experimental materials for the project "Study on Biological Functions of Nucleic Acid Lipid Nanocarriers in Microgravity Environment", led by GAN Yong's Lab at the Shanghai Institute of Materia Medica, were delivered to the ...

2025-08-29 All →

Nature Ecology & Evolution | Researchers Discover That “Less Is More”: Gene Loss Drives Adaptative Evolution in a Pandemic Pathogen

In a study published in Nature Ecology & Evolution, Daniel FALUSH and YANG Chao's team from the Institute of the Chinese Academy of Sciences, along with Jaime MARTINEZ-URTAZA's team from Universitat Autònoma de Barcelona and WANG Hui' team from S...

2025-08-29 All →

Groundbreaking Whole-Brain Imaging Reveals Glioma Heterogeneity and Vascular Disruption

Glioma, one of the most aggressive brain tumors, exhibits significant spatial and temporal heterogeneity, especially in its vasculature. This complexity has long hindered effective drug delivery and treatment outcomes. Traditional imaging techniqu...

2025-08-22 All →

Researchers Reveal How Macrophages Deploy “Fishing Nets” to Catch Distant Bacteria

For decades, immunologists pictured macrophages as armored guards that simply patrol tissues and engulf microbes that happen to touch their surface. Yet in crowded infections, most bacteria land tens of micrometres away, well beyond the reach of o...

2025-08-22 All →

Rational Design Strategies in DNA-Encoded Libraries for Drug Discovery

DNA-encoded libraries (DELs) have emerged as a transformative screening platform in the early stages of drug discovery. Their core advantage lies in the ability to covalently link billions of small molecules to unique DNA barcodes, enabling ultra-...

2025-08-22 All →