Research News
- PNAS｜Cryo-EM Structures Reveal How GnRH Activates Its Receptor, Opening Pathways for New Therapies
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Researchers Disrupt cGAS-DNA Phase Separation by De Novo Design of Allosteric Inhibitors: A Potential Therapeutic Strategy
- Researchers Develop Tracheal Targeted Nanogrid Drug Delivery Systems Visualized by Three-dimensional Pathological Mapping
- NMRExtractor: Leveraging Large Language Models to Construct an Experimental NMR Database from Open-source Scientific Publications
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Researchers Reveal Structural Basis of Prostaglandin D2 Receptor DP1 Activation and Its Implications for Drug Design
- Researchers Design Novel Reaction Description Language for Encoding Molecular Editing Operations in Chemical Reactions
- Researchers Reveal Activation Mechanism of Prostaglandin E2 Receptor EP1
- Researchers Circumvent “On-Target Apoptotic Toxicity” in RIPK3 Inhibitors via Conformational Regulation Strategy
- Scientists Discover Residue-Selective Inhibitors via Covalent DNA-Encoded Chemical Library Selection with Diverse Warheads
- Hedgehog-Interacting Protein Drives Lung Maturation and Confers Resistance to Chronic Respiratory Diseases
- Researchers Decode Neuronal CCL2 as Key Bridge Between Diabetes and Mental Disorders
- Study Reveals Metabolic Impact and Clinical Relevance of Intact N-Glycosylation in Colorectal Cancer
- Self-Assembling Glycopeptide Defeats Superbugs by Disrupting Cell Structures and Virulence Pathways
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Scientists Discover Lysine-Targeting Covalent Inhibitors via DNA-Encoded Chemical Library Selection Platform Guided by Proteome-Wide Data
- Dynamic Cap-Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease