Researchers Identify the “Northwest Passage” Mechanism of Bile Acid Transport

Bile acids are essential for digestion, metabolism, and hormonal signaling. Their circulation between the liver and intestine, known as the enterohepatic circulation, depends on...

Researchers Develop a Versatile Bioorthogonal Theranostic Platform for Precision Cancer Therapy

Targeted protein degradation (TPD) has revolutionized drug discovery by enabling selective elimination of previously ‘undruggable’ proteins through molecular glue degraders (M...

Study Develops Human-Derived AMBER Editor for Efficient C-to-U RNA Editing in vivo

In a study published in National Academy of Sciences of the United States of America (PNAS), a research team led by HAO Pei from the Shanghai Institute of Materia Medica, Chines...