Natural Polysaccharides Uptake in Intestinal Cells Relies on Clathrin/Dynamin1/Rab5-Dependent Endocytosis

Natural polysaccharides demonstrate diverse notable pharmacological activities including anti-tumor, immunomodulatory, antiviral, hypoglycemic, and anti-aging, with relatively l...

Scientists Develop Cytoplasmic ssDNA–LNP System for Longer-Lasting Antigen Expression

Lipid nanoparticles (LNPs) have become a leading delivery platform for nucleic-acid medicines, particularly messenger RNA (mRNA). Yet mRNA can be unstable in the cytoplasm, and ...

Scientists Unveil an Oral Drug Candidate VV261 against Chikungunya Virus

Chikungunya virus (CHIKV) is a mosquito-borne, positive-sense RNA virus that causes high fever and severe joint pain. Since 2004, CHIKV outbreaks have become more frequent and w...