Study Develops Human-Derived AMBER Editor for Efficient C-to-U RNA Editing in vivo

In a study published in National Academy of Sciences of the United States of America (PNAS), a research team led by HAO Pei from the Shanghai Institute of Materia Medica, Chines...

Researchers Decode Selective and Dual Blocking of Prostaglandin Receptors EP2 and EP4

Prostaglandin E2 (PGE2), a key lipid mediator, drives inflammation, pain, and cancer progression by activating four G protein-coupled receptors (GPCRs): EP1–EP4. Among these, E...

Chemerin Receptor Structures Disclose New Lipid Metabolism Mechanism

Chemerin is a key adipokine—a signaling protein released by adipose tissue—that regulates lipid metabolism and insulin sensitivity and thus is involved in many metabolic disea...